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Простое начало. Как четыре закона физики формируют живой мир - Партасарати Рагувир - Страница 69


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6 Yamamoto K. et al. Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. American Journal of Physiology-Heart and Circulatory Physiology. 2005; 288: H1915 – H1924 (2005); Wang H. et al. Shear stress induces endothelial differentiation from a murine embryonic mesenchymal progenitor cell line. Arteriosclerosis, Thrombosis, and Vascular Biology. 2005; 25: 1817–1823.

7 Landecker H. Culturing Life: How Cells Became Technologies. Cambridge, MA: Harvard University Press, 2010; Steinberg M. S., Takeichi M. Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl. Acad. Sci. 1994; 91: 206–209.

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10 Eiraku M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature. 2011; 472: 51–56.

11 Eiraku M. et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell. 2008; 3: 519–532.

12 Lancaster M. A. et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013; 501: 373–379.

13 Cepelewicz J. An ethical future for brain organoids takes shape. Quanta Magazine. 2020; January 13 (https://www.quantamagazine.org/an-ethical-future-for-brain-organoids-takes-shape-20200123/).

14 Huh D. et al. Reconstituting organ-level lung functions on a chip. Science. 2010; 328: 1662–1668.

15 McAleer C. W. et al. Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics. Science Translational Medicine. 2019; 11: eaav1386; Edington C. D. et al. Interconnected microphysiological systems for quantitative biology and pharmacology studies. Sci. Rep. 2018; 8: 1–18.

Глава 9. Экосистема внутри вас

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11 О заболеваемости холерой и ее лечении см. статьи на сайтах ВОЗ (https://www.who.int/news-room/fact-sheets/detail/cholera) и Центров по контролю и профилактике заболеваний США (https://www.cdc.gov/cholera/treatment/index.html).

12 Russell B. et al. Type VI secretion system effectors: Poisons with a purpose. Nat. Rev. Micro. 2014; 12: 137–148.

13 Об экспериментах с холерным вибрионом и его T6SS в моей лаборатории: Logan S. L. et al. The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts. Proc. Natl. Acad. Sci. 2018; 115: E3779 – E3787.

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20 Cui W. et al. Diverse communities behave like typical random ecosystems. bioRxiv. 2019 (https://doi.org/10.1101/596551); Marsland III R. et al. Available energy fluxes drive a transition in the diversity, stability, and functional structure of microbial communities. PLOS Computational Biology. 2019; 15: e1006793.